butabarbital raises toxicity of methoxyflurane by increasing metabolism. Contraindicated. Increased metabolism of methoxyflurane to nephrotoxic compounds.
butabarbital will decrease the extent or impact of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
butabarbital will lessen the extent or impact of ramelteon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.
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butabarbital will decrease the extent or impact of duvelisib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration with a solid CYP3A inducer decreases duvelisib area underneath the curve (AUC), which may cut down duvelisib efficacy.
butabarbital will lower the level or outcome of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
HydrOXYzine: May improve the CNS depressant result of Barbiturates. Management: Take into consideration a reduce inside the barbiturate dose, as ideal, when used together with hydroxyzine. With concurrent use, observe sufferers intently for too much reaction to The mixture. Take into consideration therapy modification
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butabarbital will reduce the level or outcome of atazanavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
butabarbital will minimize the level or impact check here of guanfacine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Powerful or moderate CYP3A4 inducers considerably lower guanfacine plasma concentrations and elimination fifty percent-life.
butabarbital will lessen the level or result of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Mysterious.
butabarbital will lower the extent or result of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Importance Unknown.
butabarbital will lessen the level or impact of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
butabarbital will raise the amount or effect of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.